WELCOME TO THE MUCIN BIOLOGY GROUP !
The Mucin Biology Group is one of the
major research groups of the Department of Medical Biochemistry at the
Sahlgrenska Academy, the Medical Faculty of University of Gothenburg. The group
usually consists of about 15 persons and has a genuine international
atmosphere. During the last 10 years there has most of the time been
several pre- or postdoctoral fellow from other countries. English is the language written and spoken in the
With the large grants we have obtained recently, we will expand the number of persons in the group and scientist that will work together with us and the groups of Fredrik Bäckhed and Henrik Sjövall. We already collaborate closely with Professor Henrik Sjövall
and his group as these are already colocalized. We will now expand our
collaboration with Dr. Fredrik Bäckhed and his group when it comes to
bacteria and germ-free animals.
The group is part of MIVAC (see also link to
the left) where we are very active. We also have very close contacts with the
clinical gastrointestinal unit at the Sahlgren's hospital. We meet every week for joint
seminars between clinically active physicians and we and other basic
researchers. Dr. Sara Lindén has her own group localized close to
us and we share common interest in mucins. Dr. Niclas G. Karlsson has recently
established his group at the University of Gothenburg and we share
equipment, lab. space and interest in the analysis of glycans with mass
spectrometry. Professor Susann Teneberg with her interest in bacterial
adhesion to glycans are also localized in the same premises. We all together
make up one of the largest centers for mucins, mucus biology and
glycobiology in the world.
The group has a high number of international contacts.
We are working with Professor John R. Riordan at UNC Chapel Hill, NC. (discoverer of the CFTR channel), Dr- Hugo de Jonge
(Rotterdam) on CFTR dysfunction and PDZ binding proteins and mucins, Dr Lijun
Xia, Oklahoma, on his specific glycosyltransferase knock-outs and colon
inflammation, Professor Sandra J. Gendler on the MUC1 transmembrane mucin, with Dr Ana Velcich on the Muc2-null mice, and with many more labs in the world.
The group is well equipped and we have
just installed the most advanced mass spectrometer available, a Thermo LTQ-Orbitrap with an ETD (see equipment and other pages). We are relatively well funded. The group is highly computerized and everybody working for a longer time
have their own computer.
The group are in recently rebuilt laboratories located on the bottom S-floor of the Department. This has allowed us to be
localized together with the MPE core facility that is closely connected the group, together with our mass spectrometry facility and also close
to the other groups of MIVAC.
The house is directly coupled to the animal house as well as to
the house for the Natural Sciences Departments of Biochemistry and Molecular
Biology. Close to the Department is the Swedish NMR Center currently soon
housing the only 900 MHz machine in Sweden. The Department has a tradition
of mass spectrometry back to the early 1960-ies and the laboratory is among the best equipped mass spectrometry laboratory
in Scandinavia. The Sahlgrenska Academy Core Facility proteomics facility is also located close to
our mass spectrometry
unit. We also have our own databases and other necessary software..
The group is hard working and determined to develop our international leading edge
position within mucin and mucosal surface research.
This leading edge is exemplified with the recent PNAS article on the
organization of the mucus layers in colon. Still the group has a very nice and friendly atmosphere according
to present or previous members.
If you are considering doing a post-doctoral period, a
Ph. D., or a shorter project work in the Mucin Biology Group you should
know that you are very welcome and that everybody will do their best to
help you and to create a nice time for you.
If you have any questions, do not hesitate to contact me.
Gunnar C. Hansson
Professor, head of The Mucin Biology Group