Welcome to the 2011 Homepage of the
MUCIN BIOLOGY GROUP
(MUCINBIOLOGISKA GRUPPEN)
MBC - Mucus, Bacteria and Colitis SSF Center
Lederhausen's Center for Cystic Fibrosis Research
at the
University of Gothenburg, Gothenburg, Sweden
 
NEWS DECEMBER 2011
VETENSKAPSRADET SAMVERKANS GRANT
1,600,000 SEK per year for for three years
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CANCERFONDEN
800,000 SEK per year for for three years
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Knut and Alice Wallenberg Foundation GRANT awarded to P.I. Gunnar C. Hansson
28,000,000 SEK for for five years
'The mucus layer formed by the MUC2 mucin as the habitat of the colon commensal microbiota'
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Löfswedska Stiftelsen awarded a GRANT to Lederhausen's Center for Cystic Fibrosis Research
500,000 SEK
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NIH (National Institute of Health) GRANT awarded to P.I. Gunnar C. Hansson
230,000 USD per year for three years
'The MUC2 Mucus Gel as an Innate Immune Mechanisms that Inhibits Colitis'
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SEE and LISTEN to us at:
  • November, 16: Lund University, Lund, Monday Nov 16, 12.20-13.00 (Kemicentrum), Gunnar C. Hansson; Mucins and colon inflammation
  • November, 28: Karolinska Institute, MTC, KI, Stockholm, Monday Nov 28, 13.00-14.00 (A302), Gunnar C. Hansson; Role of mucin in colon barrier function;
  • December, 7-9: Linkoping University, Linkoping, The Intestinal Barrier; Dec 7, 11.10-11.40, Malin Johansson: Role of mucus in barrier function
  • March, 4-9: Keystone Symposia, Keystone; The Microbiome and innate Immunity: Sensing teh Microbes and Damage Signals; Gunnar C. Hansson, Good Barriers Encourage Appropriate Microbiota


RECENT PUBLICATIONS
  • Johansson, M. E. V. and Hansson, G. C. (2011) Keeping Bacteria at a Distance. Science 334, 182-183.
  • Johansson, M.E.V., Ambort, D., Pelaseyed, T., Schütte, A., Gustafsson, J.K., Ermund, A., Subramani, D.B., Holmen-Larsson, J.M., Thomsson, K.A., Bergstrom, J.H., Sjoerd van der Post, S., Rodriguez-Pineiro, A.M., Sjövall, H., Bäckström, M., Hansson, G.C. (2011) Composition and functional role of the mucus layers in the intestine. Cell. Mol. Life Sci., 68, 3635-3641.
  • Pelaseyed, T. and Hansson, G. C. CFTR anion channel modulates expression of human transmembrane mucin MUC3 via the PDZ protein GOPC. J. Cell Sci. 2011 124: 3074-3083
  • Songhet, P., Barthel, M., Stecher, B., Müller, A.J., Kremer, M., Hansson, G.C., Hardt W.D. (2011) Stromal IFN-?R-Signaling Modulates Goblet Cell Function During Salmonella Typhimurium Infection. PLoS One. 2011;6(7):e22459.
  • Fu J, Wei B, Wen T, Johansson ME, Liu X, Bradford E, Thomsson KA, McGee S, Mansour L, Tong M, McDaniel JM, Sferra TJ, Turner JR, Chen H, Hansson GC, Braun J, Xia L.
    Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice.
    J Clin Invest. 2011 Apr 1;121(4):1657-66. doi: 10.1172/JCI45538. Epub 2011 Mar 7. PubMed PMID: 21383503; PubMed Central PMCID: PMC3069788.
  • Thomsson E, Persson L, Grahn A, Snäll J, Ekblad M, Brunhage E, Svensson F, Jern C, Hansson GC, Bäckström M, Bergström T.
    Recombinant glycoprotein E produced in mammalian cells in large-scale as an antigen for varicella-zoster-virus serology.
    J Virol Methods. 2011 Apr 22. [Epub ahead of print] PubMed PMID: 21540058.
  • Ambort D, van der Post S, Johansson ME, Mackenzie J, Thomsson E, Krengel U, Hansson GC.
    Function of the CysD domain of the gel-forming MUC2 mucin.
    Biochem J. 2011 May 15;436(1):61-70. PubMed PMID: 21338337.