CURRICULUM
VITAE
Gunnar C.
Hansson
Address:
Stenungsundsgatan 8
416
74 Gothenburg
Address
work:
University of Gothenburg
Department of Medical
Biochemistry
Box
440/Medicinaregatan 9
S-405
30 Gothenburg
Social:
Married, 3 children (1979, 1982,
1990)
Basic education:
Studentexamen Växjö
(natural sciences) 1970
Medical
education:
Medicine kandidat 1972
M.D.
(läkarexamen) 1976
Medical licence
Licence to practice
medicine in
Scientific
training:
Part time 1972‑1976
Full time 1976‑1981
-PhD. (medicine
doktorsexamen) 1981
-Docent in Medical and
Physiological Chemistry (Medical Biochemistry) 1983
Scientific
positions:
-Post-doc. position
(forskarassistent) 1984-1987 at the Department of Medical Biochemistry
-Associate
professor (Senior Lecturer for Research) of Molecular Biology at the Medical Faculty
of Göteborg University, 1987-1996. Permanent-tenured position (universitetslektor).
Professorships
-Appointed
as Associate Professor (‘Biträdande professor’) in Molecular Biology University
of Gothenburg, 1996-1998
-Full
professor of Medical Biochemistry (medicinsk och fysiologisk kemi), Department of Medical Biochemistry,
University of Gothenburg, 1998 - present.
Abroad:
-Visiting
fellow Feb.1983-June 1984, National Institute of Health,
-Visiting scientist, Mayo Foundation;
Positions as
physician:
Physician
in chronic illnesses clinic (1 month), ear-nose-throat clinic (3 months), paediatrics
(university clinic, 3 months), blood bank (3 months), and psychiatry (University
clinic, 3 months). Surgery and Internal Medicine at
Member of:
·
The
Royal Society of Arts and Sciences in Gothenburg (KVVS) 2012 –
·
The
Royal Academy of Sciences (medicine) (KVA) 2015 –
Awards:
·
Axel Hirsch price, Karolinska Institutet, Stockholm 2018
·
The
Royal Swedish King Medal 8th size with Serafimer ordens ribbon for meritorious
achievements in Medical Research, especially Cystic Fibrosis, 2021
Honorary
positions:
§
Started
PhD-student organisation at Medical Students Union in Göteborg. Its first chairman
(ombudsman) 1979-1980. 1981 its secretary.
§
Member of one of
the Medical faculty committees (biochemistry) evaluating Ph.D. examinations,
1992-1998. Chairman of the committee 1994-1998.
§
Regular member
of the Medical faculty board for basic education (grundutbildningsnämnd)
1997-1998.
§
Vice Chairman of
Department of Medical Biochemistry 2000 - 2005
§
Head of Ph.D.
student education 2000 - 2006.
§
Board member of
Centre for Gastroenterological Research, Göteborg University 1998 - 2005
§
Chairman of Science
committee of Department 2006 - 2008.
§
Board member of
The Swedish Society for Biochemistry and Molecular Biology 2004 - 2010.
§
Board member of
The Swedish Society for Mass Spectrometry (SMSS) 1997 - present
§
Chairman of The
Swedish Society for Mass Spectrometry (SMSS) 2005 - 2010
§
Member of the
board for Sahlgrenska Academy (Faculty board for Medical -, Dental -, and
Nursery School) at Göteborg University, 2007 – 2016
§
Member of the
board for Erica Lederhausens Foundation, 2009 – present
§
Study and
proposal (Utredning) for Coordination of Biological Mass Spectrometry in Sweden
- BioMS. Research Council – infrastructure. 2012-2013.
Teaching:
Long
experience of teaching at undergraduate (Medical school, Dental school,
Pharmacy school) as well as several Ph. D. courses. Large experience in
teaching administration.
Bibliography:
See separate list.
Published
>300 scientific publications. 8 of these have been published in Proc. Natl.
Acad. Sci. USA, 29 in The Journal of Biological Chemistry.
From
ISI, h-index 68 (Feb 2022).
Most cited publication:
The inner of the two Muc2 mucin dependent mucus layers in colon is devoid of bacteria. Proc. Natl. Acad. Sci USA, 105, 15064-15069
Cited 1182 times today
and stadily >100/year, 2020 cited 139 times.
Selected invitations
to give plenary presentations (last 5 years):
2018
North Atlantic Respiratory Conference, Lousanne,
Switzerland , Jan. 17-19, 2018 (GCH)
Gut-directed Bioactive for Next Generation Nutrition
Convening, Gates Foundation, Seattle, WA. July 17-19, 2018
Alfred Benzon Foundation Symposium on
Glycotherapeutics, Copenhagen Aug. 27-30, 2018
Key Symposium on Innate Immunity, Oxford, UK, Oct.
26-28, 2018
14th Biennial Congress of the European Association of
Oral Medicine (EAOM), Gothenburg, Sweden, Oct. 27-29, 2018
University of Colorado, Denver, CO, Invited lecture,
Oct. 17, 2018
University of Würzburg, Germany, Invited lecture, Nov.
20, 2018
Institue Pasteur, Paris, France, Invited lecture, Nov.
26, 2018
2019
Dept. Immunology Seminar Series, Univ. Gothenburg,
Feb. 1, 2019
Gordon Research Conference: Cilica, Mucus and
Mucociliary interactions, Lucca Italy, Feb 17-22, 2019, Plenary lecture
ECF Basic Science Conference, Dubrovnic, Kroatia. Mar
27-30, 2019
2019 Harvard Digestive Diseases Center’s (HDDC’s)
Spring Symposium in Boston, MA. April 2, 2019
COPD Symposium 2019, University of Gothenburg, May 7,
2019
Vertex Master Class, Arlanda Stockholm, May 9, 2019
Center for Glycobiology, Copenhagen, May 10, 2019
North American CF Meeting, Vermont, June 23-26, 2019
Mucin in Health and Disease, Cambridge, July 29-Aug 2,
2019
2020-2021
Next-Gen Immunology, Nature Conference, Wiessmann
Institute, Rehovot, Israel
Most meetings cancelled due to Corona
2022
European CF Basic Science Conference, Albufeira,
Portugal, Mar 30 – April 2.
EMBO|EMBL Symposium: Innate Immunity in Host-Pathogen
Interactions. July 17-20, Heidelberg
Mucins in Health & Disease International
Conference, 27-29 July, Utrecht
Berchtesgaden Microbiome Science Days, Sept 9 10,
Berchtesgaden, Germany
Dynamic Hydrogels at Biointerfaces, Oct 6-7, Berlin
Organisation of
international meetings:
Mucus and mucins,
Gothenburg 1995. About 150 participants.
Mass spectrometry in
biology, Hindås 1997. About 50 participants.
XIIIth
Interantional Cystic Fibrosis Congress, Stockholm 2000, About 1500 participants
Innate immunity in the
gastrointestinal tract, October 2003, About 90 participants
CFTR in the
gastrointestinal tract, November 2005, About 90 participants
Symposium at
Posttranslational
modifications, Annual SMSS symposium, April 2008, About 100 paricipants
Annual
scientific meeting for SMSS, 2007, 2008, 2009
Vice-chairman
for FEBS 2010, joint meeting organized by Sweden-Norway in Gothenburg
Vice-chairman
for European Cystic Fibrosis Conference 2014, Gothenburg
Nordic
Glycobiology meeting, 2017 Gothenburg. 100 participants
Royal
Academy of Scinces “Next challenge-Impact of Glycosalation”, Nov. 11, 2019,
Lund. 150 participants
Science Policy
Article
on funding of medical research in Dagens Nyheter, main Swedish newspaper, 2001
On
Cystic Fibrosis, SVD 2018
Editorial Board
Biochemical Journal 2003 -
2020
Glycobiology 2006 - 2020
Current major
external funding:
·
Wallenberg
Foundation, 2017-2023, SEK 5 800 000/year
for 5 years, Molecular structure of mucin domains and roles of their interactions in
mucus of the intestinal and respiratory diseases. Finishes June 30, 2023
·
Melinda and
Bill Gates Foundation 2019-2022, USD
749,770 for 3 years, In Vitro and In
Vivo Mucus Screen for LOPAC and Natural Product Libraries. Finish June 30,
2022
·
The Swedish Science
Research Council 2018-2021; SEK 1 800
000/year for 5 years; Biochemistry and function of mucins and related
molecules in the respiratory and gastrointestinal tracts. Highest score possible.
·
LUA/ALF, Mucus in Diseases - COPD, Cystic Fibrosis,
Crohn’s, and IBS, 2022-2024, SEK 1 000
000/year
Finished (major)
·
European
Research Council, 2016 – 2021, Advanded ERC, SEK 4 800 000/year for 5 years, The role of mucins and mucus in the diseases cystic fibrosis, ceoliac
disease and ulcerative colitis.
·
National Institute
of Allergy and Infectious Diseases, National Institue of Health (NIH) 2016-2021
USD 305 614/year for 5 years. The MUC2 Mucus Gel as an Innate Immune
Mechanisms that Inhibits Colitis
·
The Swedish
Cancer Foundation 2018-2020; SEK 1 250
000/yearfor 3 years; Mucus in Diseases - Cystic Fibrosis, COPD, UC, IBS,
and Pancreatic Cancer
·
NATIONAL
INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, NIH 2012-2016 USD 300 000/year for 5 years. The MUC2 Mucus Gel as an Innate Immune
Mechanisms that Inhibits Colitis
·
Wallenberg
Foundation, 2012-2017, SEK 28 000 000
for 5 years, The mucus layer formed by the MUC2 mucin as the habitat of the colon
commensal microbiota
·
The Swedish
Foundation for Strategic Research, 2010-2015, SEK 30 000 000 for 5 years, The colon mucus layers as the
first innate immune barrier.
Established
the Consortia of Mucin Biology Groups (MBG) at Dept. Medical Biochemistry
Supervision of
PhD.- completed thesis (year of
graduation and current position)
1. Dan Baeckström 1995, Dept. Medical Biochemistry in
Gothenburg
2. Jing-Yang Mu,
1996, together with prof. Ove Lundgren
3.
Ke Zhang, 1997, bioinformatic scientist at Ceres Inc., CA,
(http://www.ceres-inc.com).
4.
Niclas Karlsson 1997, professor,
Oslo.
5.
Rein Sikut, 1998, head of immunology group at a biotech. company
6.
Noomi Asker, 1998.
7. Magnus Axelsson, 1999, Clinical Chemistry,
8.
Kristina Thomsson, 2000.
9.
Fredrik Olson, 2002.
10.
Christian Andersson 2003, AstraZeneca, Gothenburg
11.
Sirle Laos 2005, researcher Barcelona, Spain
12. Martin Lidell 2006, universitetslektor at Inst.
Biomedicine, UGOT
13.
Emily Malmberg, 2006,
14.
Jessica Holmén Larsson, 2006, AstraZeneca
15.
Tiange Lang, 2007, post-doc in China
16.
Malin E.V. Johansson, June 2009, PI, Universitetslektor, Medical Biochemistry, MBG
17.
Jenny Gustafsson, May 2012, Shared with Henrik Sjövall, post-doc PI, post-doc VR Physiology, MBG.
18.
Thaher Pelaseyed, Nov. 2012, PI, Researcher, SSMF, MBG.
19.
Joakim Bergström, Dec. 2014, Lab. Director at astraZeneca
20. Sjoerd van der Post, Dec. 2014, PI, post-doc position
VR, MBG.
21. Karolina Sjöberg Jabbar, Nov. 2018, post-doc at
Broad/Harvard
Former
and current international and national Post-docs in the laboratory:
1.Daniella
Steel (from
2.
Rein Sikut (from
3.
Klaus Godl, (from
4.
Julia Fernandez-Rodrigues Univ. Vigo, from
5.
Cristina Weinberg (from
6.
Malin Bäckström, Univ. Gothenburg, (from
7.
Elin Grahn, Univ. Gothenburg, post-doc in Örebro
8.
Kristina Thomsson, Univ. Gothenburg, Proteomics Core Facility
10.
Iris Härd, Karolinska Inst., left science.
11. Ana Rodriguez Pinero, Vigo University Spain, AstraZeneca
12.
Thaher Pelaseyed, established his own lab. at Dept.
13.
14.
Babu Sharamsha, India, post-doc. at UNC Chapell Hill, NC
15.
Jessica Holmen Larsson, researcher at Clinical Neuroscience, Univ. Gothenburg
16.
Malin Johansson, Univ. Gothenburg, established her own laboratory 2014.
17.
Anna Ermund, Lund University, Scientist in my lab.
18.
Sjoerd van der Post, in my lab. PI, on VR Starting grant
19.
Harriet Nilsson, deceased
20.
Catharina Wising, Sweden, Scientist in industry.
21.
Andre Shutte, Germany, post-doc Heidelberg, Germany
22.
Christian Recktenwald, Germany, Scientist in my lab.
23. Hedvig Jakobsson, Sweden
24. Robert Rojas, Brasil, established his own lab. in
Chile
25.
Liisa Arike, Tallin, Estonia, Post-doc in my lab.
26.
George Birchenough, London, UK, PI, VR, Wallenberg Center, in MBG
27.
Evelin Berger, Germany, Post-doc in my lab.
28.
Hannah Schneider, Germany, Proteomics core facility, Gothenburg.
29.
Lisa Wuerner, Germany, Scientific writer
30.
Jenny Gustafsson, Sweden, PI Dept. Physiology, Gothenburg
32.
Joan Fernandez, Spain, University Teacher Spain.
33.
Joakim Bergström, Sweden, To industry.
34.
Sergio Tillo Muyo, Spain, Post-doc in my lab.
35. Brendan Dolan, Dublin, Ireland, Post-doc in my
lab.
36. Dalia Fakih, Beirut, Lebanon, AstraZeneca.
37. Aaran Lewis, London, UK, To industry
38. Melania Giorgetti, Italy, Pharmacy Industry
39. Pablo Gallego, Spain, Post-doc in my lab.
40. Maria José Bonete, Spain, Post-doc in my lab.
Senior Scientist working in my laboratory
1. Drs. Jean-Francois and Daniel Bouhours (from
2. Prof. John R. Riordan (from
3. Prof. Sandra J. Gendler (from
4. Prof. Carlos Flores (from Chile) 5 month 2018
Current staff in
the laboratory
6 post-docs
One nurse
External PhD.
examiner
1. Peter Aagaard-Nielsen, 1997, Copenhagen, Denmark
2.
Helle Hassan, 1999, Copenhagen, Denmark
3.
Torunn Thingstad 2000,
4.
Hans Wandall, 2004, Copenhagen, Denmark
5.
Mads Peter Agervig Tarp, 2006, Copenhagen, Denmark
6.
Susan McNally, 2010, Dublin, Ireland
7.
Zang Yand, 2012, Århus, Denmark
8.
Vignesh Venkatakrishnan, 2014, Sydney, Australia
9.
Elisabeth Haugstad, 2015, Trondheim, Norway
10.
Marlene Andersson, 2016, Uppsala, Sweden
11. Benoit Chassaing, 2019, HDR defense, Paris, France
12.
Thomas Daugbjerg Madsen, 2021, Copenhagen, Denmark
Patents
1. USE OF ALGINATE OLIGOMERS IN THE TREATMENT OF CYSTIC
FIBROSIS AND OTHER CONDITIONS ASSOCIATED WITH DEFECTIVE CFTR ION CHANNEL
FUNCTION, US Patent: DEHN40.006APC
2. A PROTEIN BASED ON ZG16 TO BE USED AS A MEDICAMENT, EU
patent granted 15 798 074.9, withdrawn
3. Calcium binding compounds
based on gammacarboxy glutamate. US Patent
10,035,821 B2, July 31, 2018, EPO
pending
Göteborg 2022-12-07
Professor